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Whats up, chances are you’ll keep in mind me from a [very long post + flowchart](http://nervewing.blogspot.com/2020/10/new-drugs-designing-novel.html) to assist within the design of arylcyclohexylamines. Nicely I am again and I’ve completed it once more, this time for the Diarylethylamines, the category of molecule that provides us dissociatives similar to Ephenidine, Diphenidine, and MXP. It has been critically underexplored and there is loads of potential for growth inside that household! Different attention-grabbing medicine come up there too, similar to lefetamine, a broadly abused pharm in many years previous that has all however pale into obscurity.
[The full article can be found here](http://nervewing.blogspot.com/2020/12/new-drugs-diarylethylamines.html)
[An image of just the flowchart can be seen here](https://i.imgur.com/v7rVSoR.png)
[A pdf of the flowchart can be downloaded here](https://gofile.io/d/tYPnG1)
It is loads of dense phrases and appears very advanced however I hope this can assist inform growth inside this fascinating class of chemical substances! I omitted a piece on the place I like to recommend the best way to develop them additional, simply because so few knowledge factors exists for these compounds that it is arduous to discern viable leads for additional growth. We actually solely have blocks of knowledge for three dissociatives, it is arduous to tug any sample from that, and in my thoughts, any variations are welcome and price investigating!
Which compounds would you prefer to see developed?
Bought one other publish on an much more obscure household of dissociatives coming down the pipe soon- the [Dioxolanes](http://nervewing.blogspot.com/2020/05/obscure-and-unknown-dioxolane.html).